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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b6c1e4978debbf7fea3f2998b68edb6bb92518da8f885786b3b85f1f3b4717' 
  AND token = 'kRMlPinw3cfxetrFDsuVEwG/RNW8Wc6mjusGbn1+aKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}