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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad45d56640ae7460c9860f1a6752c4e0cb2b69024c935e8d1107227b6e7634f2' 
  AND token = 'Kq3tbSc8Ad8YuSynPkRgQQQQp1wDd2vvCfy8/WcutB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}