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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c68f0102ad1da1ba8a12cb81a0fba6f5591f36270b40bb74f295adb7c1c50b7' 
  AND token = 'fwP6dvxb7Dj/z/+i123OG0JTUYwf6+eRjaL3RUSq7fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}