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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad9b5daa603fdab61e98d3571680d7d0fa0f92aa4358d2d1f9a4fedd9ff3834e' 
  AND token = 'EfAf4Lyy8W1LWvSPZUPePh8wucl4BR2WdOFVtbfhZW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}