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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e26d1ed9209add1550ab4899f74c386eef11799c1dc45d78ce88755b8f40bf7' 
  AND token = 'qAfFrbPxWoSWF7LG1rZgRnQFsOlYFe37mDn8Nk5+vLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}