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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54982e6a1e55571b033c06e912c300fe9effd6df44add3c74d94c619faa7a67d' 
  AND token = 'HLWOIhUB0wMiDxrF1aTTDdhwV7WGHCdZodg+8RCSs2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}