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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbde591325deed40d82b28dbee7cd05f64d7e9ebce3723b9fdff1490dc4efdd4' 
  AND token = 'Z6+FGDpGJTVEUpF4Id+Ql8jCSm0Ji0S9VxIUy5ZOPaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}