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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd11d3a0122ebf203f981311181a504888aeec8fa63a45e8f0363fcbf0e3441f0' 
  AND token = 'uSjzExYWA4n7CQ3Y5Tk/VJGGrgv0DGzpbRlAoGT3ThE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}