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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5edc77b3e745ce9fbda5b9290c306599702ef15dad5b52999785ad18c352cb' 
  AND token = 'TBriqA1o5Cffkn72KkuJr8eyv4n1GM6lOUQyrHhiYMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}