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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653b73968a69e20ad93f0213ffc0aa183d678b29261e239c889f52e6d60be52f' 
  AND token = 'sKtromSj8Aqztrp2pMCtT/+v99F0fbUgDsexxe3J2m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}