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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c371f1bf46891d6dbf704fc38e9dd2db27d714b5cb33af900d94712f66158925' 
  AND token = 'V1h5rfYxTTi1aDDg6gM6dA05Tny0kxMxajdHeuX04Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}