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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6283e5f9831055e58ec2b8b1c5b40e26bbdf68e9185419875a854ac175ad389' 
  AND token = 'MS9hiISCIXxbuwtcEnVPrMrWKTUscP+apmK4M4Vh2qU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}