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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7716c91e312f7f34217306f1890c960df822e1d9a6d060afa6516993fd637e2d' 
  AND token = 'nPVDhdBN2I5QKmNMe3vUg1mTlk1y2JN/aRoJlo9DLiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}