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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf0e9e313eb5770b8ccc8226809527b4ab6fac896af7b3a45d1b611130da320' 
  AND token = '2mqiQhD42HnFeAJ5x8fQ8VxpLVAXvDXpLBi2240hr+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}