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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acd109d9aa08f15dc736d7a2d6737384b9e2e9ebcb714b7a4a5b48fe92c06b5a' 
  AND token = '+O6NitjAmHxqs9l52vv8c/iCPlwE2MTxe3jDABtcSLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}