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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a0abde4ef65d2974e68dd6c05ba1319f3d645e91436200a6fcde1e0292ccc6' 
  AND token = '44pcLKQhnvNPUBMeAH3HHxfnpO9oauepIXCkcm9QB6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}