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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91421be48d7c56efba729bdd30162b240926f44f541d17f0f6693cc21014fc27' 
  AND token = '5CEwFZRBF4VIWFatA9nfZGCAKbCcwoD6K5sebGmOhKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}