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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c105a5e2699442c97be246965d748a06ba04335698b736de9c9e1029532a925d' 
  AND token = 'KnQfznYu93tGsAbcwMkuhc2/P6qbrc97C3nOL5fwLpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}