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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0380f91fc284b1b544b2dc60f1abe3d4d85a6de8ad77dc34aa2eb83ff8ec7eb5' 
  AND token = 's2Xjvlp6H5rlqdoi5ZkkozBKRUWwr22TIs2Xj9mpyII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}