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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9c6743647d10d409ee4b06c3cc6099fb2b70284b6cee9d9d2ff0dd565eb4795' 
  AND token = 'qWd28GiopHkU31AdrbNp5i1tsPVh7YWOMwHNSAYg+OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}