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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dda69727afe52f5fda107358de1dc727d898a895859bfb97ef44f8cb81f727b' 
  AND token = 'CXPkjFJf6t1Ku0L8mYOsNen9V/CF9BbBvgulnjmlaZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}