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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e513a5d4d36a004b5b01f017a51c42f8f33fd9f96073a16f50d026036d80976' 
  AND token = 'KKEJ4gt02laxbg/O1Esj5xvDKT9UgM0+UgYv5suPQMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}