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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4db8524dded9f191c32295172314db03a62c74d5ea1dcb240c432a5e5ea187' 
  AND token = 'h5Fp/0JGXW6E8X5mWSUr8y9g+TR3ltD65/66s/9u2ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}