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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf18dfe0a4704e23680c340057743a09db6a52febd4df3196dc0c70623d4e5cb' 
  AND token = '9tRc1C+0t7pbhK3DjV1/bgbABFKnEbI8aQl4nOuHjYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}