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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7a13ddd6f64ebf3582aa3886e49a7ecc925f37cf3a63976e383536175a34d81' 
  AND token = 'fs5OzSrPEdpHLCdPp7ddPPSs79/Pq4mQtb8Eb3HQ8Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}