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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a663f6e603839fd402cf1d5980f4d68211eee02dfe64058ae02c4e5fdea112' 
  AND token = 'J0giVZhh6f+iKQUfswToBhMUQ7A4JslxF6/j9iypXq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}