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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d3ed6272b9df49adcbb59dbf6c4301ba66c3b1d7cbd259df93a7d59f30541b' 
  AND token = 'vVEjeLFREdP27BEJ8BKUXjfUE39zxYV1qxUd387GnvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}