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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03f3978ae89a65d8d2c64c7fd3957f9f9d8020f58fe83fb727f97ec244402d2b' 
  AND token = '40/PaO7AdxYMPVWM6Hg3DBkdGWCelQJ/ZVPOilAfB/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}