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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bed018d3b9070e8521e1d47ac6e32ffd3b293e415992f7d05a2d2e7cdd5d33' 
  AND token = 'GoBRrfNlWd6AI6xu3sESSFzxVUjfu2quIyYYnkOma/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}