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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4060f2f1a494822dbcbdaa9346ed13cf1555d5a700eed277ab9425aecba0be87' 
  AND token = 'PcDZt8n2neqFwZvmmKVNpliqLveKK19j6d9ZMQ6g1yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}