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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '362b9753b58e9865f37cb3aae4cb4fce914404b219c42b86939ff3c118d341e8' 
  AND token = 'AdVvFkjW9oCL88fbcAjUIfXDW35Rxi3jTuP24y51EvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}