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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65401280feb7c59de452ab6231322308113817cd651a63741347c12b34a6c6cd' 
  AND token = '9ER1wUynaCAKFsR2A2m1tYXZdTpHWhHOG1tUm7+4uCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}