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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5743b15d5b501630a04160a4fbc61f4065953d4df454dc3e8e4da4d29e63b036' 
  AND token = 'BReGrfmJoffMJ47WA9vbxseqak3B4cYiNw5HSyjBz0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}