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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e02a3b83bd79f532834a279e97421b3d0b997a79a60c0d9989ca94fe6582a29' 
  AND token = 'b8KBFRWg8N9FnFt165WfWf+M1DO5AdSgGOEyu0j8i/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}