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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8da81dd85e22dbd60d72c0bb5c54aa778eb7ee25bab07352e2bc04d5a529c928' 
  AND token = 'QKGUHmuJVK/Pco3Jmz5A9+T8jo+5Wwa5h6ScBfRsW/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}