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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a52985bffca0688f80a3c09356f91a49e82f7cbaa21a862542ff94102f86444' 
  AND token = 'Wp+CeaH+mS3Gbo86PR7o3WtzT5dFISdLq7Yv5Hykcfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}