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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dbc88d569c57e00a45ab4222d6307153780caf15044d4c117e0dbc49710b3e0' 
  AND token = 'c6bYoIod+mP/XZHEDNAsNc2a7UjCw0blojvruJYs76Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}