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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '415e194095dc92e08c96f68b7d7a1fdb62ebe05ac590870f7406972254cd9caa' 
  AND token = 'sjK4WVy8WN5REHU8mxGPx7pZzVS4CblkXR0D75hTvuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}