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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b36b83cc465d6fc42fb2e3bbf83a28c11302d04aef80f82a928599661c452d' 
  AND token = 'DJA45mmnHcW35xRbN6S6ZC9uMh5D7dwGKeGYSTD7jTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}