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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '899acbe5e794f4817fef3c8f426301808803cd00c5fdbbe3636d4041614ce0dc' 
  AND token = 'JkfXSXBixTJ/j2cdypvX9OW0nM699HF8DocMIA30LjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}