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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7d762357b7059a48117eada0da2ffc4abbba1b70ecf66f1c010e2b38b766af' 
  AND token = 'KeVR+I0NEvkWoouKWhPS59aw6NzFCP8ICZHlNMnu7Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}