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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61a63fd249b8727607253c81e602b95ef3c94598b11326e1e7848be32b36a16' 
  AND token = 'P7TmKbRYkjTy344FebfxMPsutc/C+v1IF5WFz3tCgJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}