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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356c6c972ad52126ec95e59473086407d55f67bf9da6700d0e43e357cfd40bba' 
  AND token = 'YN9fOENvrOPTwnzDArj52ppBnOtDdz53c4zBJ8sTurw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}