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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186a201aede752ef91125dc0c555c931780afc18b795ca04ad1be8e5029babd2' 
  AND token = '2IF+7r3eEFkboFfexyDGMDFcGvl0ZZsnTEgeuW4SHko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}