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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4fd92cd297e9c09976d9d4dcf60f0c8eefb97fd15fab257a7be78da425bba5a' 
  AND token = 'qqzdVJYa1NI8tOp+aBYHak6HdYMRp0RB5ei06IWqrlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}