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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83311704d8ea5d71058f5d8ebe9327a0652629d77d53fccdc4eecce2218e301c' 
  AND token = '+++MxUugwtrr9eN3UuOQvGxTsvaSbI0TLoihs4duRnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}