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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ed467d895c0d5f0c5957188f654addcdbd93808b2e67ec28c8f563e6fbfa56' 
  AND token = '8MdKhFqyGJ5H5ZkYuMX2yboGdzjcYiFebVJPUdhPXs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}