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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19b5a5f115242e260fe28a9c5dac691b9b0683350a379f5e338dd68e4da42fe2' 
  AND token = '67CatWhzIOCqDETRZeh5NPGbumuUZuTxuwEQQV3HSlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}