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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a153a83a874f992fe6a239d71238a025d0838ec6b2a039bb413da705c37e44' 
  AND token = 'xPNb96AscLxX5LLKxfixDpp2uHkRS25cQGaBViJ5LLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}