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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e16988aadc52ae8e5c2299f9247e2b48e074df318c2eebff31592cff4996f45' 
  AND token = 'qQHy9fe4sYuNqb+N22jrsux0TK47ufXzG93B9Je/LIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}